Study Type


Study Purpose

The DYNAMMO research study aims to understand how exercise affects the way our bodies convert the food we eat into energy.

About the Study

Once enrolled, participants will be randomly assigned to either an exercise or standard of care program. Both groups will receive exercise training. Both groups require 4 overnight stays in the Pennington Biomedical Inpatient Unit.

Study Design

Number of Visits: 

  • 2 screening visits
  • 6 study visits, including 4 overnight stays
  • 5 days per week for 12 weeks for exercise


  • Medical history
  • Height and weight
  • Vital signs (pulse and blood pressure)
  • EKG
  • Questionnaires
  • Urine Pregnancy Test (women of child bearing potential)
  • Blood draws
  • Exercise Tests
  • Insulin Sensitivity Test
  • Oral Glucose Tolerance Test
  • DXA Scan (to measure bone, muscle and body fat)
  • Muscle Biopsies
  • Resting Metabolic Rate (RMR)

Study Qualifications

To qualify for this research study, participants should:

  • Be between 18 to 60 years old
  • Have a Body Mass Index (BMI) between 25 - 50 calculate your BMI
  • Not be a smoker

* You may not qualify for this study based on other eligibility criteria not listed. The study coordinator will go over this information in detail.

Study Duration

Participation in this research study will last approximately 18 weeks.


Compensation of up to $1200 is offered for the completion of this study.

Study Contact

If you are interested in volunteering for this research study, click here to screen online, call 225-763-3000 or email clinicaltrials@pbrc.edu.

If you are a physician referring a patient, click here.

If you think you may be eligible, please click the button below to screen online.


Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.


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